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Profile picture for user jim.lefevere
Principal
Genevius Health Advisors
United States

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Jim Lefevere

Jim Lefevere is a globally recognized leader in life sciences and HealthTech, with more than two decades of experience driving digital transformation, commercialization, and strategic growth across the pharmaceutical, MedTech, and diagnostics industries. Throughout a 24-year career at Roche, Jim held multiple global leadership roles spanning marketing, digital health, product development, and medical affairs innovation.

At Roche, Jim led some of the company’s most transformative global initiatives, including a $127 million ROI enterprise-wide digital marketing transformation and the launch of 19 award-winning global campaigns. He pioneered the use of patient-centric marketing and introduced social media to the diagnostics industry, helping to reshape how the company engaged healthcare professionals, patients, and digital opinion leaders. His work delivered over $175 million in new revenue through digital-first go-to-market strategies and contributed to building Roche’s first global digital platforms for customer engagement and product support. Jim also played a key role in developing new business franchises and commercial ecosystems, leveraging real-world data, and digital technologies to support product innovation and chronic disease management.

Since leaving Roche in October 2024, Jim has focused his career on advising high-growth organizations at the intersection of healthcare, technology, and innovation. He is the Founder and Principal of Genevius Health Advisors, a boutique consultancy that provides AI-powered commercialization strategy, go-to-market planning, product launch support, and revenue acceleration services for life sciences, biotech, and MedTech companies. Genevius distinguishes itself by offering not only strategic insight but also hands-on execution, helping clients turn complex challenges into measurable, scalable outcomes.

Jim also serves as fractional Chief Strategy Officer (Consultant) for Axonal.AI, an emerging leader in AI-powered medical affairs and evidence generation. In this role, he helps shape the company’s commercialization and product strategy, guiding their efforts to bring advanced analytics, predictive insights, and real-time data intelligence into medical communications and decision-making support for life sciences companies.

Deeply committed to advancing healthcare innovation, Jim actively mentors and advises early-stage start-ups through leading accelerator programs. He is a mentor for:

Paratus Digital Health Accelerator, a BARDA-backed program hosted by MATTER Health

Innosphere Ventures, supporting science- and technology-based startups

Indiana BioCrossroads, Indiana’s life sciences innovation and entrepreneurship initiative

Through these programs, Jim works with HealthTech and biotech founders to refine their value propositions, strengthen commercialization strategies, and scale new products that improve patient outcomes and system efficiency.

With a deep foundation in both global enterprise and agile start-up environments, Jim brings a rare combination of strategic thinking, operational expertise, and digital fluency. He is frequently called upon to speak, write, and advise on topics including AI in healthcare, go-to-market strategy, digital health acceleration, and the future of patient engagement.

Jim holds executive education credentials in Disruptive Strategy and Sustainable Business Strategy from Harvard Business School, a certificate in Leadership in an Exponentially Changing World from MIT Sloan, and a degree in Journalism from Indiana University.

Today, Jim continues to collaborate with innovators across the health ecosystem—from established biopharma firms to digital health startups—to help them navigate complexity, accelerate innovation, and achieve meaningful growth in a rapidly evolving marketplace.

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